Portland is the largest city in the U.S. state of Oregon and the seat of Multnomah County. It is a major port in the Willamette Valley region of the Pacific Northwest, at the confluence of the Willamette and Columbia rivers. The city covers 145 square miles (380 square kilo- meters) and had an estimated population of 647,805 in 2017, making it the 26th most populous city in the United States, and the second-most populous in the Pacific North- west. Approximately 2,424,955 people live in the Portland metropolitan statistical area (MSA), making it the 25th most populous MSA in the United States. Its Combined Statisti- cal Area (CSA) ranks 18th with a population of 3,160,488. Roughly 60% of Oregon's popu- lation resides within the Portland metropolitan area.